Our antibodies are designed with human biology,
not around it

Our Platform

Infinimmune holds the world’s largest database of millions of paired heavy+light sequences, and countless antibody variants sourced from a continuous pipeline of diverse healthy and diseased human donors.

Hundreds of validated targets systematically mapped for specificity and functionality.

1 Week

With our Complete Human sequencing technology® and Anthrobody® library-on-B-cell platform, we discover fully paired, end-to-end sequenced, antigen-specific antibody sequences from up to 300 million B cells across 350+ targets.

Using native specificity, cross-reactivity, and affinity of clonal and ultra-rare antibodies captured by the Anthrobody platform, we select optimal candidates for further development.

With our GLIMPSE™ antibody language model we combine in silico characterization and diversification with wet lab validation to optimize affinity, potency, and developability, with DC generation in as little as 8 weeks.

Benchmark development candidates in established animal models for efficacy, pharmacology, and pharmacokinetics.

Downselect
DC Selection
Engineer
Screen & Sequence

Output

Powerful and safe biologics with novel sequence and structure.

Our pipeline converts evolutionary successes into breakthrough medicines

Reach out to partner with us
Program
IFX-101
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IFX-101
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IFX-201
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IFX-201
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IFX-301
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IFX-301
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IFX-401
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IFX-401
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IFX-501
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IFX-501
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Immunome (partnership)
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Immunome (partnership)
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Target
IL-22 (msAD)
IL-22 (msAD)
IL-13 (msAD)
IL-13 (msAD)
APRIL (IgAN)
APRIL (IgAN)
IL-17F (UC)
IL-17F (UC)
Undisclosed
Undisclosed
Undisclosed
Undisclosed
Status
Internal
Internal
Internal
Internal
Internal
Internal
Internal
Internal
Undisclosed
Undisclosed
Undisclosed
Undisclosed
Discovery
Optimization
Efficacy
Candidate
CMC
Phase 1
Stage: Phase 1
Stage: Phase 1
Stage: Efficacy
Stage: Efficacy
Stage: Efficacy
Stage: Efficacy
Stage: Efficacy
Stage: Efficacy
Stage: Undisclosed
Stage: Undisclosed
Stage: Undisclosed
Stage: Undisclosed
Undisclosed
Program
IFX-101
Stage: Phase 1
Target →IL-22 (msAD)
Status → Internal
Learn more
Learn more
IFX-101
Stage: Phase 1
Target →IL-22 (msAD)
Status → Internal
IFX-201
Stage: Efficacy
Target → IL-13 (msAD)
Status → Internal
Learn more
Learn more
IFX-201
Stage: Efficacy
Target → IL-13 (msAD)
Status → Internal
IFX-301
Stage: Efficacy
Target → APRIL (IgAN)
Status → Internal
Learn more
Learn more
IFX-301
Stage: Efficacy
Target → APRIL (IgAN)
Status → Internal
IFX-401
Stage: Efficacy
Target → IL-17F (UC)
Status → Internal
Learn more
Learn more
IFX-401
Stage: Efficacy
Target → IL-17F (UC)
Status → Internal
IFX-501
Stage: Undisclosed
Target → Undisclosed
Status → Partnered: Undisclosed
Learn more
Learn more
IFX-501
Stage: Undisclosed
Target → Undisclosed
Status → Partnered: Undisclosed
Immunome (partnership)
Stage: Undisclosed
Undisclosed
Undisclosed
Learn more
Learn more
Immunome (partnership)
Stage: Undisclosed
Undisclosed
Undisclosed
Undisclosed

Experts across immunology, AI, and drug development, working as one.

Our team combines deep immunology,  AI, technology and drug development expertise to systematically mine human repertoires and bring the highest-quality antibodies into the clinic, drawing on leadership experience from teams at 10x Genomics, Pacific Biosciences, the Broad Institute, Pfizer, Amgen, Genentech, Chemocentryx, IgM Biosciences, NGM Bio, and Compugen.

Team
Wyatt McDonnell, PhD
CEO & Co-Founder
Tim Sullivan, PhD
Chief Business Officer
Mike Gibbons, PhD
Chief Scientific Officer & Co-Founder
Katie Pfeiffer, PhD
Chief Technology Officer & Co-Founder
Lance Hepler, PhD
Chief Information Officer & Co-Founder
David Jaffe, PhD
Infinimmune Fellow & Co-Founder
Maya Kotturi, PhD
Vice President, Preclinical Development
Andrew Hill, PhD
Senior Principal Scientist, Computational Biology
Lee Rivera, PhD
Senior Principal Scientist, Preclinical Development
Ringo
Chief Morale Officer
Clinical Advisors
Emma Guttman
MD, PhD
Jonathan Silverberg
MD, PhD, MPH
Andy Blauvelt
MD, MBA
Anthony Slavin
PhD
Mike Howell
PhD
Board
Wyatt McDonnell, PhD
Board Chairman & CEO
Katie Pfeiffer, PhD
Board Director & CTO
Mike Gibbons, PhD
Board Director & CSO
Neela Patel, PhD
Independent Board Director
Benjamin Kim, PhD
Board Director, Playground
Investors